alexa DRD and GRIN2B polymorphisms and their association Parkinson’s disease patients

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DRD and GRIN2B polymorphisms and their association Parkinson’s disease patients

Impulse control disorder (ICD) and behaviours (ICB) represent a group of behavioural disorders that have become increasingly recognised in Parkinson’s disease (PD) patients who previously used dopaminergic medications, particularly dopamine agonists and levodopa. It has been suggested that these medications can lead to the development of ICB through the abnormal modulation of dopaminergic transmission and signalling in the mesocorticolimbic dopaminergic system.

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