Historical dose prescription in BT is based on Manchester system that was designed to deliver a specific dose to a reference point (point A), independently of three-dimensional spread of tumour volume. This point has no relationship with tumour position and real threedimensional tumour extent.
Citation: Meregalli S, Guerra L, Zorz A, Bonetto E, Brenna S, et al. (2013) Intracavitary Brachytherapy in Cervical Carcinoma: The Role of F18-FDG-PET in Treatment Planning. J Nucl Med Radiat Ther S6:015. doi: 10.4172/2155-9619.S6-015