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Oxygen derived free radical result in reproductive impairment through oxidative damage to biomolecules in the testicular cell, with mitochondria being the main target of free radical attack. Since oxygen radicals are needed for many metabolic and physiological processes, equilibrium between radical production and their antioxidant-linked inactivation is required to preserve health. Thus, reproductive impairment is one of the results of an imbalance between free radical production and antioxidant defense.
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