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Technologies in molecular imaging have developed from a standalone modality to multi-modality method. Multi-modality imaging fuses two or more imaging modalities into a hybrid system emerging as a crucial means to provide more precise details than single only imaging modality. For brain imaging, the representative molecular imaging modalities are including the MRI, X-ray computed tomography (CT), PET and SPECT. The strength of multi-modality molecular imaging lies in combing the morphologic and functional processes, paving the way to further insight into molecular pathology of human diseases.
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