Radiation-incuded sarcoma (RIS) is a well known complication following radiation therapy. The incidence of radiation-induced sarcoma in the head and neck region is rare. The incidence of RIS in post-irradiated bone is reported to be in the range of 0.03% to 0.8%. There are also large variations in reported latency period between completion of radiotherapy to the development of the sarcoma. This can be as short as three years and as long as five decades.Treatment of radiation-induced sarcomas may include surgical resection, chemotherapy, further irradiation (external beam or brachytherapy), or a combination of the above.