Prevention of schizophrenia is difficult as there are no reliable markers for the later development of the disease. There is tentative evidence for the effectiveness of early interventions to prevent schizophrenia.
While there is some evidence that early intervention in those with a psychotic episode may improve short-term outcomes, there is little benefit from these measures after five years. Attempting to prevent schizophrenia in the prodrome phase is of uncertain benefit and therefore as of 2009 is not recommended.
Cognitive behavioral therapy may reduce the risk of psychosis in those at high risk after a year and is recommended by the National Institute for Health and Care Excellence (NICE) in this group.
Another preventative measure is to avoid drugs that have been associated with development of the disorder, including cannabis, cocaine, and amphetamines.
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