Dengue virus infection is extremely common worldwide. Neurologic involvement is not very common, but several forms of central and peripheral nervous system impairments have been described in patients with dengue. Several neurologic manifestations of dengue can be found in patients with dengue. Headache can result from systemic inflammation or meningitis. Altered sensorium occurs as a consequence of encephalitis, encephalopathy, acute demyelinating encephalomyelitis, or stroke. Para- or tetraparesis can be seen as a consequence of Guillain- Barré syndrome, myositis, or hypokalemic paralysis. The early recognition of neurologic the pattern of neurologic involvement is important because some of these conditions require specific and prompt therapeutic interventions. In the present paper, we review the different forms of dengue-associated neurologic disordersand propose a practical approach to treating patients with dengue associated neurological symptoms.