In silico Screening for Identification of Novel Aurora Kinase Inhibitors by Molecular Docking, Dynamics Simulations and Ligand-Based Hypothesis Approaches

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Subject wise Global Events

In silico Screening for Identification of Novel Aurora Kinase Inhibitors by Molecular Docking, Dynamics Simulations and Ligand-Based Hypothesis Approaches

Aurora kinase family members are involved in a wide variety of cell cycle events including centrosome separation, cytokinesis, kinetochore formation, spindle assembly, chromosomal segregation and microtubule dynamics. Typically, dysfunction of Aurora proteins is associated with aneuploidy, cell death and mitotic arrest, leading to tumorigenesis. This spurred a vast interest to identify pharmacologically active small-molecule inhibitors of Aurora proteins. In this study, we isolated four novel inhibitors through virtual screening and docking analyses.

Citation: Batool S, Ferdous S, Kamal MA, Iftikhar H, Rashid S (2013) In silico Screening for Identification of Novel Aurora Kinase Inhibitors by Molecular Docking, Dynamics Simulations and Ligand-Based Hypothesis Approaches. Enz Eng 2:106. doi: 10.4172/2329-6674.1000106

Share this page

Subject wise Global Events

In silico Screening for Identification of Novel Aurora Kinase Inhibitors by Molecular Docking, Dynamics Simulations and Ligand-Based Hypothesis Approaches

Recommended Journals

Subject wise Open Access Journals

Conferences by Country

Medical & Clinical Conferences

Conferences By Subject