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Poornima Sharma, Aung Oakkar, et al. of Tate Cancer Center, University of Maryland Baltimore Washington Medical Center ressolved a case Contemporary Management of Non-Appendicular Mucinous and Signet Cell Colorectal Cancer in Community Setting. They conclude Mucinous and signet cell histology is a clinicopathological distinct type of colorectal cancer that carries a negative impact on patient survival. Despite multimodality management and advance in chemotherapy, stage IV mucinous-signet cell colorectal cancer has a dismal prognosis. New treatment strategies for mucinous-signet cell cancer are needed. (Full-articles)