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Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world . Risk factors such as hypertension, metabolic syndrome, cigarette smoking, diabetes mellitus, elevated glucose and cholesterol levels, and obesity or being overweight are the top causes of death globally. The Emerging Risk Factors Collaboration incorporating 160,309 study participants demonstrated the independent predictive value of C-reactive protein (CRP) for coronary heart disease (CHD) and stroke, the clinical utility of CRP and fibrinogen in CVD risk prediction, and the limited role of adding the novel lipid markers apolipoprotein A-I, lipoprotein (a), apolipoprotein B, and lipoprotein-associated phospholipase A2 to traditional lipid measure.
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