Lipocryolysis has already been established as a safe and effective technology. Though there is broad consensus that lipocryolysisis not a harmful technology, very little has been said about the functionality of those adipocytes that remain in the body after the procedure. The aim of this study has been to roughly assess the lipolytic activity of the adipocytes that suffer lipocryolysis. Rat white adipocytes were isolated, tempered and exposed to isoproterenol and cell count and glycerol concentration were measured. We found that the adipocyte count was significantly higher in the samples not exposed to cold and that adipocytes were still capable of lipolysis after the treatment. These findings suggested that cold can damage adipocytes and that it may not impair lipolysis in the adipocytes that remain in the body after the treatment.