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Role of Leptin in Immune Dysfunction in WNIN Obese Rats

Immune dysfunction leading to increased susceptibility to infectious diseases is often seen in both obese animal and human subjects [1]. However, no specific factor/mechanism has been attributed to this, though a correlation between reduction in total body fat and impaired immunity was established in a wide range of species including humans, suggesting the role for adipose tissue in altered immune function [2,3].

 

Citation: Bandaru P, Rajkumar H, Upadrasta VP, Nappanveettil G (2013) Role of Leptin in Immune Dysfunction in WNIN Obese Rats. Endocrinol Metab Synd 2:116. doi: 10.4172/2161-1017.1000116

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