In the present study, clinically significant EDS was frequently encountered among patients with depressive symptoms, and a significant association was observed between depression and EDS. Thus, careful investigation of daytime sleepiness in depressed patients is advised during clinical evaluation. Incidentally, there are no facilities in Nigeria for proper evaluation of sleep complaints. Concerted effort should be made by appropriate authorities to establish facilities for dealing with sleep complaints. Besides, enough personnel in the field of sleep medicine in the country should be encouraged. It is expected that with adequate and proper facilities in place, the number of personnel in this field will gradually increase. In the meantime, clinicians should be aware of the magnitude of the problem of EDS, particularly, among depressed patients and be proactive in its management so as to reduce the burden of depressive disorder in the developing countries.