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Examination of the FDA Warning for Statins and Cognitive Dysfunction

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Examination of the FDA Warning for Statins and Cognitive Dysfunction

Statins are widely prescribed in the United States for primary and secondary cardiovascular risk reduction and constitute an estimated $26 billion dollar per year market for pharmaceutical manufacturers . The numbers of patients receiving statin therapy is likely to increase in the coming years based on the dissemination in 2013 of the American College of Cardiology/American Heart Association’s (ACC/AHA) updated clinical guidelines for the assessment and management of blood cholesterol for primary and secondary prevention . Although the new guidelines simplify clinical treatment strategies, they promote a broader risk assessment tool which may increase the numbers of patients between the ages of 20 – 79 eligible for statin use for primary prevention to an estimated 46 million Americans .

Citation: Sahebzamani FM, Munro CL, Marroquin OC, Diamond DM, Keller E, et al. (2014) Examination of the FDA Warning for Statins and Cognitive Dysfunction. J Pharmacovigilance 2:141.

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