The frequent co-occurrence of depression and anxiety has long been recognized. As many as 40-50% of patients with major depression have comorbid anxiety disorders [1-5]. Evidence suggests that the combination of depression and anxiety leads to worse outcomes and response to treatment compared to either disorder alone [6-11], highlighting the importance of research that examines the interactive effect of depression and anxiety on the broad spectrum of possible outcomes.
Citation: Dotson VM, Szymkowicz SM, Kirton JW, McLaren ME, Green ML, et al. (2014) Unique and Interactive Effect of Anxiety and Depressive Symptoms on Cognitive and Brain Function in Young and Older Adults. J Depress Anxiety S1:003