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Recent evidences support that leukotrienes (LTs) are important molecules in innate and also adaptive immune responses. Some features of these lipid mediators include their ability to be synthesized by a variety of cell types, their diverse antimicrobial actions, and their interactions with other important mediators. More specifically, leukotriene B4 (LTB4) displays protective effect against infections, such as fungal pneumonia, those caused by helminths and bacterial peritonitis.
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