alexa New Insights into Estrogen Signaling

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New Insights into Estrogen Signaling

Many important molecules have a dual role in the human body. As a key representative, 17β-estradiol (E2) a fundamental steroid hormone, has diverse physiological functions in different parts of the body, while its cellular proliferation or mitogen role is somehow implicated in the induction and promotion of cancinogenesis. E2 actions in the reproductive system via the classic mechanism, which is a nuclear receptors involved genomic-associated pathway, to affect the expression of target genes. Recent years, the fact that estrogens function in other systems such as brain, especially via non-genomic pathways, have drawn attention.

Citation: Peizhong M (2014) New Insights into the Estrogen Signaling . Bioenergetics 3:e120. doi: 10.4172/2167-7662.1000e120

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