alexa Evidence of Two Ciliated Epithelial Cell Subsets in Mouse Airways

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Evidence of Two Ciliated Epithelial Cell Subsets in Mouse Airways

Patients with asthma-associated airway epithelial damage exhale increased levels of nitric oxide (NO). However, the distribution of endothelial NO synthase (eNOS) in mouse airways remains to be controversial. In the present study, mouse lung sections were stained using antibodies against secretoglobin 1A member [1] (Scgb1a1), acetylated tubulin (ACT), and eNOS. We found that club cells in the mouse airways are immunoreactive toward eNOS. In addition, to the best of our knowledge, for the first time, two subsets of ciliated cells that differ in their expression of eNOS were observed to reside in the mouse airways. Both subsets of ciliated cells survived naphthalene-induced lung injury. These data will help clarify a controversial issue of whether ciliated cells contribute to epithelial maintenance in the airways.

Citation: Huaiyong C, Qi W, Xin S, Ruo C, Junping W, et al. (2014) Evidence of Two Ciliated Epithelial Cell Subsets in Mouse Airways. Bioenergetics 3:114. doi: 10.4172/2167-7662.1000114

 
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger
 
adwords