Oral ulcerations pain management depends on severity of the ulcers. Chlorhexidine digluconate together with oral antibiotics or oral prednisone was found to be useful. Kaposi sarcoma can be treated using radiotherapy, laser or surgical intervention. Highly active anti-retroviral therapy (HAART) forms part of therapeutic management in these patients. Good oral hygiene and plaque control is vital to prevent secondary infections. Parotid gland enlargement often causes xerostomia (dry mouth) which can lead to dental caries. A salivary substitute can be used together with thorough oral hygiene and dietary control is essential. Additionally, xerostomia can lead to candidiasis.