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This is a paper which examines the causes, symptoms, predisposing factors, prevention, and control of neonatal tetanus in African c hildren. Neonatal tetanus wa s found to be the leading cause of death among neonates. It was found to result mainly from social a nd environmental factors, such as poor hygiene, use of non - sterile materials in treating the stump of umbilical cords in newborns, poor attendance to antena tal clinic, high - level illiteracy, and non - utilization of tetanus toxoid immunization. Based on the findings recommendations were proffered, wh ich include: legislation in favor of anti - tetanus immunization as prerequisite for contracting marriages in c ourt s in African countries; strategic and vigorous immunization exercise should be embarked upon at various levels; public enlightenment campa ign targeted at exposing the nature of the disease to the entire public be carried out by ministries of health at stat e and federal level, Non - Governmental Organizations, and other health agencies.