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Evaluation of Carbohydrate and Lipid Metabolism and Risk of Obesity in Children after Brain Tumors Treatment

The aim of the study was to assess the carbohydrate and lipid metabolism disturbances as well as weight in children after brain tumors treatment. The study included 33 boys (53.2%) and 29 girls (46.8%) aged 11.6 ± 3.9. 22 patients underwent treatment for tumors of hypothalamic-pituitary(h-p) area: IA–surgery(19/22); IB–surgery and radiotherapy(3/22). 40 patients were treated for tumors outside the h-p area: IIA– with surgery, chemo-and radiotherapy(22/40); IIB–only with surgery(15/40); IIC–patients treated for optic nerve glioma with chemotherapy(3/40). BMI was assessed before and after the treatment. OGTT, HbA1c, lipid profile and WHtR after treatment were assessed. Indices of insulin resistance: HOMA-IR, Quickie, Matsuda and de Fronzo were calculated.

Citation: Okonska M, Adamkiewicz-Drozynska E, Korpal-Szczyrska M, Birkholz-Walerzak D, Mysliwiec M (2014) Evaluation of Carbohydrate and Lipid Metabolism and Risk of Obesity in Children after Brain Tumors Treatment. J Steroids Hormon Sci 5:137. doi: 10.4172/2157-7536.1000137

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