Transplantation of bone marrow-derived mesenchymal stem cells (MSCs) is a promising therapy for spinal cord
repair. Its potential, however, is limited by poor survival of the cells in the damaged nervous tissue. A number of studies have tried to improve MSC transplant survival, yet often with limited or short-term effects. Survival enhancing strategies include optimizing timing of transplantation, suppressing the immune response, transplantation within a scaffold to limit anoikis, reducing reactive oxygen species and/or macrophages,
Citation: Oudega M, Ritfeld G (2014) Bone Marrow-derived Mesenchymal Stem Cell Transplant Survival in the Injured Rodent Spinal Cord. J Bone Marrow Res 2:146.