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Mixture models provide flexible means of handling heterogeneity in data. The possible latent structure suggested by mixture model analysis should be carefully examined using designed experiments. Sample size determination is an important and difficult step in design of experiments. We investigate the sample size calculation for the modified likelihood ratio test for binomial mixture models arising in genetic linkage analysis. Read moreomicsonline.org/open-access/sample-size-calculation-for-the-modified-likelihood-ratio-test-in-genetic-linkage-analysis-2155-6180.1000205.pdf
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