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Meta Description: Inflammation is sometimes manifested as fever and symptoms such as anorexia and malaise, locally as redness, warmness, swelling and pain in the affected area. Though inflammation was closely linked to the immune system it was an independent system. Inflammation is a functional manifestation of innate immunity, whose immunocompetent cells include monocytes/ macrophages, dendritic cells, neutrophils in a broad sense, and humoral factors such as chemokines.