In recent decades, large amount of diverse xenobiotics have been released into the marine environment as a consequence of anthropogenic (agricultural/urban/industrial) activities. These substances include heavy metals, herbicides, pesticides, fungicides, plasticizers, polystirenes, phenols, dioxins and organotins. This environmental pollution represents a serious hazard for marine animals since the impact on their endocrine systems may result in reproductive problems. In fact, it has been shown that xenobiotics may affect the mechanisms of fertilization and early development, leading to disruption of normal reproductive function in adulthood . In this respect xenobiotics are considered as endocrine disruptors (EDs) since they are capable of disrupting the endocrine system of animals, including fish, wildlife, and humans due to an interference with the normal mechanisms of hormone action.