Once you hit 40, you may find that drinking like you did in your 20s leaves you feeling worse for wear in the morning. That's because alcohol hits you harder as you get older and everything from muscle mass to over-the-counter meds are to blame for the more painful hangovers.“All of the effects of alcohol are sort of amplified with age”. A person's body composition can start to change as early as his or her 30s. In addition to losing muscle and gaining fat, he or she also has less body water and may be dehydrated. People with a higher percentage of body fat and less body water tend to feel the effects of alcohol more strongly than those with greater muscle mass.