alexa New formulation of Diltiazem Hydrochloride

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Recommended Conferences

cardiology and cardiovascular medicine

London, UK

World Cardiology Summit

New York, USA
New formulation of Diltiazem Hydrochloride

Graded extended-release diltiazem (CARDIZEM" LA) (GRD) is a new formulation of diltiazem engineered to provide more precise blood pressure control than traditional antihypertensive agents. Unlike other diltiazem once-daily formulations, CARDIZEM" LA is a tablet formulation. Its pharmacokinetic profile differs from that of CARDIZEM" CD, another extended-release formulation of diltiazem, in that GRD exhibits a smoother drug-release profile with a "one-peak" plasma concentration time curve. Clinical results demonstrate therapeutic efficacy throughout its 24-h dosing interval, regardless of time of administration; however, compared with morning administration, evening dosing results in significantly greater bioavailability. The trial results, demonstrating consistent 24-h efficacy and excellent tolerability, suggest that GRD may be a beneficial option in the treatment of hypertension and angina.

  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger
Top