Chronic thromboembolic pulmonary hypertension (CTEPH) is the result of clot persistence and fibrosis in the pulmonary vasculature after acute pulmonary embolism. This condition leads to elevated pulmonary pressures and eventually right heart failure. Patients are often severely limited by exertional dyspnea and can experience significant morbidity and mortality when left untreated. The condition is also associated with impairment of left ventricular diastolic function and filling. Pulmonary thromboendarterectomy (PTE) is currently the only curative treatment for CTEPH and greatly alters the clinical course of the disease.