alexa Angiotensin-II Induced Reactive Oxygen Species

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Angiotensin-II Induced Reactive Oxygen Species

ROS play a crucial function in the advancement and also servicing cardiovascular vascular diseases, specially hypertension. The relation in between ROS and also hypertension has been shown in a number of types of experimental hypertension.

 

Accumulating evidence has suggested that the key mechanism through which Angiotensin II (Ang II) influences blood pressure is via its ability to activate ROS signaling pathways. Ang II, through stimulating angiotensin AT1 receptors, connected with NAD(P)H oxidase, the major source of ROS generation.

 

Despite several studies that were built up with regards to ROS/Ang II signaling, there is certainly still a lot to elucidate the function connected with ROS throughout neurogenic hypertension. The present article mainly discussed some recent findings documenting about the signaling mechanisms of Ang II-induced ROS in neurogenic hypertension and therapeutic target.

 

View more at:  https://www.omicsgroup.org/journals/specialissue-hypertension-open-access.php

 
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