Folliculitis Decalvans (FD) is a rare neutrophilic inflammation of the scalp characterized by painful recurrent purulent follicular exudation resulting in primary cicatricial alopecia. Although it is not an infection, bacterial superantigens may trigger inflammation and antimicrobials, namely tetracyclines, have been tried previously with good results and are often the first therapeutic approach. There are also anedoctal improvements reported with isotretinoin, dapsone, adalimumab and infliximab, topical tacrolimus, ndYag- LASER and photodynamic therapy. Most of our FD patients are treated with minocycline. However, in south European countries tetracycline is avoided from May to October due to its hyperpigmentation potential. Thus, an antimicrobial drug effective in FD but without photosensibilization potential would be optimal. The beneficial effect of azithromycin in acne is well known, used both in monotherapy and in combination with isotretinoin. The authors present a case series of 19 patients with FD treated successfully with azithromycin in monotherapy.
Citation: Andre MC, Soares RO (2015) Effective Treatment of Folliculitis Decalvans: Azithromycin in Monotherapy. Hair Ther Transplant 5:131. doi: 10.4172/2167-0951.1000131