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Syphilis is a systemic disease caused by the spirochete Treponema pallidum. The disease has been classically divided into a series of stages based on clinical findings. The first stage of syphilis, known as primary syphilis, is marked by the presence of a chancre (a painless indurated ulcer with sharp borders that usually resolves within 3 to 6 weeks) at the site of inoculation (usually the genitals). Secondary syphilis, the stage of spirochaetemia, is characterized by systemic symptoms (fever, headache, myalgias, lymphadenopathy), mucosal lesions, hair loss and the presence of a generalized maculopapular scaly eruption on the torso and extremities. The palms and soles are affected in 60% of cases. Tertiary syphilis is characterized by cardiovascular, neurologic and gummatous lesions. In HIV positive patients the simultaneous manifestations of primary and secondary syphilis is not uncommon because the chancre is likely to persist into the secondary stage.
Citation: de Sousa ICVD (2013) Simultaneous Primary and Secondary Syphilis Associated with Syphilitic Alopecia and Folliculitis in an HIV Positive Patient. Hair Ther Transplant 3:108. doi: 10.4172/2167-0951.1000108
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