alexa Role of Atopy in Nasal Polyposis

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Role of Atopy in Nasal Polyposis

Heridatary disorder marked by tendency to develop immediate allergic reactions to subsatnces. It consists of inherited immunoglobulins that predisposes a person to allergic diseases. Temporary relief is provided by bleach baths. Atopy is also known as Eczema. Patients with sino-nasal complaints presenting to an allergist’s or otolaryngologist’s practice frequently are diagnosed with conditions including allergic rhinitis (AR) and chronic rhinosinusitis (CRS). Furthermore, patients with CRS are pheotypically classified as CRS with and without nasal polyposis (CRWwNP and CRSsNP, repspectively). There is an intuitive sense that atopy is an underlying etiologic factor in the development of CRS, particularly CRSwNP. Certainly, many patients with CRS will have atopy. AR is observed in approximately 50% of CRS patients [1] versus 15-20% in the population at large [2]. However, this clinical association does not prove causality and may reflect a selection bias by which patients with symptoms of CRS, presenting to an allergist’s or otolaryngologist’s practice are more likely to undergo allergy testing.

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