alexa Healing through Translational Medicine

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Healing through Translational Medicine

 Healing of broken bones in mice feat which can replicate in humans, that can make people with fractures can be free from their casts a lot sooner. This has huge implications in broken bones is a big problem. This technique helps in fusing bones and many other surgeries that depends on bone growth and bone healing to succeed. A lot of the surgeries we do depend on bone growth and bone healing and a lot of the failures of surgery have to do with the fact that the bone never heals or never fuse. It isn't limited to bone injuries which play in tissue repair and tissue regeneration also includes blood, neural and cardiac cells. The research to create translational medicine from the lives of animals that can regenerate on their own, such as zebrafish and flat worms. Scientists already knew that this capability was partly due to a class of proteins called Wnt proteins. Though mammals don't have the same innate ability to regenerate, the researchers speculated that, with a little help to develop translational medicine from Wnt proteins.

The researchers actually conducted two experiments, both testing the idea that tissues might heal faster if the Wnt signal was ramped up. The first used a genetic approach, involving mice that had been genetically engineered to respond better to a Wnt signal and then administering purified Wnt via fat particles known as liposomes.The second strategy involved raising levels of the Wnt protein in normal mice. Both groups of mice had sustained bone injuries.
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