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Reversal therapy treats the underlying causes of cholesterol accumulation and plaque rupture such as high cholesterol levels, smoking, excess weight, an unhealthy diet, lack of exercise, high blood pressure, diabetes and stress, by catching coronary heart disease early. Reversal therapy makes use of PET (Positron Emission Tomography), a noninvasive test that gives a better picture of a person's real risk of suffering a heart attack. PET testing can diagnose coronary artery disease early on, when treatment can make more of a difference for the patient's long-term survival.