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Lymph node status is considered the most important prognostic factor in breast cancer diagnosis, together with tumor size, histological grade, angiolymphatic invasion and the detection of hormone receptors and HER-2. Studies have shown that the chances of survival of many patients worsens with the increased detection of positive nodes, since the probability of finding a predictive positive node increases with the number of lymph nodes examined. There is no consensus as to the minimum number of lymph nodes to be dissected for accurate staging, especially in cases of pN0.
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