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Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-sulfonate (NQS)
A rapid, simple and sensitive method for the determination of finasteride using sodium 1,2-naphthoquine-4- sulfonate (NQS) has been developed. The method is based on the fact that a brown product can be formed by the reaction between finasteride and sodium NQS in a buffer solution of a pH 13.0. Beer’s law is obeyed in the range 2-14 μg/ml of finasteride at maximum wavelength of 447 nm. |
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