alexa Genetics of Antiphospholipid Syndrome

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Genetics of Antiphospholipid Syndrome

The term "antiphospholipid syndrome" has been proposed to describe the association of arterial and venous thrombosis, recurrent fetal loss, and immune thrombocytopenia with a spectrum of autoantibodies directed against cellular phospholipid components. Because of the antigen spesificity of antiphospholipid antibodies (aPL) and the pathophysiology of thrombosis in antiphospholipid syndrome (APS) are heterogeneous and multifactorial, a single scenario cannot explain the mechanisms of thrombophilia or pregnancy morbidity in patients. Investigation of the clinical epidemiology of APS is in its early stages.

 

CitationHancer VS (2011) Genetics of Antiphospholipid Syndrome. Human Genet Embryol 1:e103

 
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