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The deposition of material in solid, liquid or gas phase on the sensor surface causes frequency variations proportional to the mass or viscosity/ density product of the substance. The main advantages of the QCM are its high sensitivity and resolution, fast response-recovery time, high dynamic range, low power consumption and relatively small size (from several mm to a few cm quartz crystals). These specific features allow in situ detection of biological interactions such as antigenantibody or receptor-ligand, as well as ppb concentrations of various compounds in biological suspensions.
Citation: Esmeryan KD (2015) Detection of Biological Environments for Endometrial Stromal and Mesenchymal Stem Cells Growth through a Quartz Crystal Microbalance Based Biosensor. Biosens J 4: 120.
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