We report the case of a 57 year old female patient presenting with longstanding diffuse ankle pain. SPECT-CT was useful in making the diagnosis of an intraosseous ganglion of the posterior talus. The patient was treated with posterior arthroscopic debridement of the cyst via a two portal approach and grafting with an injectable synthetic bone graft substitute (PRO-DENSE®). The patient experienced rapid relief of pain and made a quick recovery. The surgical technique is discussed as well as a review of the current literature.
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