alexa Selection of Polymeric Excipients for Poorly Soluble Drugs

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Selection of Polymeric Excipients for Poorly Soluble Drugs

 Pharmaceutical drug delivery systems consists of variety of additional constituents other than its active pharmaceutical ingredient (API) required for pharmacological activity [1]. These constituents are defined as excipients by International pharmaceutical excipients council and are required to be properly evaluated for safety before included in delivery systems [2]. Excipients, although pharmacological inert are a key determinant of delivery systems performance. They are included in a delivery systems not for their direct therapeutic action, but are added to the delivery systems to either aid in processing during its manufacture (for e.g., vehicles, co-solvents, anti-adherents, polymers), protect, support and enhance stability, bioavailability and patient acceptability (for e.g., anti-oxidants, preservatives, disintegrants, coatings,sweetening agents, flavoring agents), assist in product identification (for e.g colorants), or enhance other attributes of the safety and effectiveness of the drug delivery system during its storage and use

Citation: Chauhan H (2015) Selection of Polymeric Excipients for Poorly Soluble Drugs. J Develop Drugs 4:e140. doi: 10.4172/2329-6631.1000e140

 
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