alexa Targeting Lymphatic Vessels with Photodynamic Therapy

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Targeting Lymphatic Vessels with Photodynamic Therapy

Lymphatic vessels ablation after PDT is strongly related to the basic mechanisms involved in PDT. Basically, PDT works due to three different biological mechanisms: (1) first the photochemical reaction acts directly against target cells, inducing a direct cytotoxic activity; (2) second, PDT promotes the shutdown of surrounding blood and lymphatic vessels; and (3) third, PDT stimulate immune system against tumor cells. It is worth to note that some authors demonstrated that it is possible to establish PDT conditions to specifically destroy lymphatic vessels. Read more...


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