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Adventitious agents are those that are not inherent in the production of biopharmaceuticals. Microbial adventitious agents, Microbiocidal agents, help for inactivation of viruses, bacteria, fungi, mycoplasma, bacterial spore and sometimes prion. Bovine spongiform encephalopathy (BSE) agents, abnormal prions, are also potential adventitious agents. Adventitious agents can be introduced during establishment of cell lines, cell culture/fermentation, capture and downstream processing steps, formulation/filling, and even during drug delivery Therapeutic biotechnology products must have excellent safety characteristics
Citation: Hideharu Shintani (2014) Hazardous Effect Free From Decontamination. Chem Sci j 5:e103.
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