alexa Igg-Reactivity of Intravenous Immunoglobulin Preparations

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Igg-Reactivity of Intravenous Immunoglobulin Preparations

We read with interest the study by Néron and Roy [1] in which, they analysed the characterization of a commercial Ä°ntravenous Ä°mmunoglobulin (IVIg) preparation by screening its interaction with 9484 proteins of human origin. They used the technology of protein array analysis and identified that 67 proteins are strongly recognized by the immunoglobulin G (IgG) present in IVIg. Néron and Roy [1] obtained acceptable reactivity for heat shock proteins, HLA-DR, thyroglobulin, CD16a (FcγRIIIa receptor), CD64, interleukin-1β, lamin A/C and ferritin, which are all related to immune-modulatory properties of IVIg. To our knowledge very few studies have analyzed the repertoire of IgG reactivities contained in IVIg preparations. In a study by Bussone et al.

 

Citation: Ozturk OG, Kibar F (2013) Igg-Reactivity of Ä°ntravenous Ä°mmunoglobulin Preparations. Biochem Anal Biochem 2:133. doi:10.4172/2161-1009.1000133

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