In world of today, cardiovascular disease is the greatest threat to human life and health. The pace of current remarkable progress in clinical and basic research during the past decade is such that notable improvement in the quality and length of life, for those at risk for cardiovascular disease, can be confidently predicted. Death rates from cardiovascular disease declined 20% in past 20 years, but today millions of US residents have a history of heart attack, chest pain, or both (American Heart Association). Moreover, cardiovascular disease remains the nation's leading cause of death, claiming nearly 1 million lives each year. As the population ages, cardiovascular disease will have an ever greater human and economic impact. Thus, research for improved predictors of cardiovascular disease and improved therapies for prevention and cure must be the goal. Despite the progress that has been made, the importance of cardiovascular research in today's world cannot be overemphasized.