These abnormalities result from one or a combination of factors, including an autoimmune mechanism, chronic inflammation, the effect of therapy, and complicating infections. Hematological abnormalities such as anemia, thrombocytopenia, and leukocytopenia are observed in Systemic Lupus Erythematosus (SLE). Patients with SLE sometimes develop Hemophagocytic Syndrome (HPS), which is characterized by pancytopenia or bicytopenia in the peripheral blood and histiocytic hemophagocytosis in the bone marrow and remainder of the reticuloendothelial system.

Citation: Kondo M, Murakawa Y, Sumita Y, Moriyama M, Honda M, et al. (2015) Concurrent Occurrence of Hemophagocytic Syndrome and Myelofibrosis in a Case of SLE. J Clin Case Rep

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