A current focus of pharmacogenomic research is to explore the effect of inter-individual genetic differences on the pharmacokinetics, pharmacodynamics, efficacy, and safety of drug treatments. The ultimate goal of these efforts is to develop personalized, genetic-based strategies that will optimize therapeutic outcomes. Ensuring drug efficacy and safety are unremitting challenges for drug manufacturers and public health organizations worldwide. It has been estimated that, when all of the drugs in the market used to treat common diseases are considered, only 25% to 60% of patients exhibit the expected pharmacological response.
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