DNA Repair Genes in Cancer Progression

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DNA Repair Genes in Cancer Progression

Loss of function mutations or expression alteration in genes of the DDR machinery and in genes involved in DNA repair execution, which are downstream activated, have been extensively associated with cancer development, progression, malignancy grade, and patient’s prognosis and survival.


Citation: Sousa JFde, Valente V (2015) DNA Damage Response and DNA Repair Genes in Cancer Progression: Good or Bad Guys? Brain Disord Ther S2:004.

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