Human Complex Disease Genetics

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Human Complex Disease Genetics

Many pioneering works have inspired researchers to stay up-todate on synthetic and system biology. Several cases that were originally thought to be exceptionally difficult, if not impossible, have been carried out successfully, such as Craig Venter’s creation of the world’s first synthetic life form. At a system level, nucleic reprogramming succeeded in frog half a century ago (reviewed in [1]); but doubts about whether or not this was impossible lingered until 40 years later, when a cocktail of four transcriptional factors systematically reprogrammed the somatic cells to stem cells.

Citations: Zhang Y (2013) Synthetic and Systems Biology: Toward Achieving Impossible Missions and Deciphering Human Complex Disease Genetics. Curr Synthetic Sys Biol 2:e102.

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