Despite its popularity, increasing dietary protein appears to have modest effects on weight loss. Furthermore, the proportion of total energy from protein that facilitates weight loss in nutritionist-recommended moderately energy-restricted diets is not clarified. We studied the association between protein intake and weight loss in obese men and women with cardiometabolic risk factors. A total of 158 subjects with abdominal obesity and at least 1 other metabolic syndrome risk factor were randomized to follow a low glycemic load diet high in protein [LGLHP] or a low fat diet with normal protein (LFNP). Weight loss (mean, 4-5 kg) was similar between groups after three months. The groups were combined and dietary intake was assed with a 7-day food record after three months. A general linear model was performed to test the association between dietary intake and weight loss in the combined group.

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