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Microparticulate drug delivery systems have been studied by the researchers for several years for various applications including targeted drug delivery, reduced drug toxicity and enhanced bioavailability of drug molecules. These microparticles can range from 1-200 μm for most of these applications. These micron sized drug delivery systems can be prepared using different techniques, such as, spray drying, emulsion method, jet milling, adsorption and solvent evaporation, fluidization/ solvent precipitation, phase separation and interfacial polymerization methods. Literature validates that various polymers have been used to prepare microparticles using these techniques, ranging from natural polymers (albumin, gelatin, chitosan, starch, amylodextrins, cellulose derivatives etc.) to synthetic polymers (poly glycolic acid- PLGA, poly vinyl alcohol-PVA etc.) based on the study requirements.
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